S144 Quality Of Life In Idiopathic Pulmonary Arterial Hypertension Is Associated With Quadriceps Function And Size

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Quality of life in pulmonary arterial hypertension

sion is likely if the velocity is more than 3.4 m/s (estimated systolic PAP > 50 mmHg) with or without additional variables [2]. Both underestimation and overestimation of the estimated systolic PAP frequently occur. PAH is a debilitating and progressive disease with a tremendous psychosocial and economic impact for patients. A high prevalence of anxiety and depression (up to 40 %) is reported ...

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Spleen size in idiopathic and heritable pulmonary arterial hypertension.

BACKGROUND It is unknown whether the spleen size correlates with disease severity and outcome in patients with idiopathic and heritable pulmonary arterial hypertension (PAH). OBJECTIVES To determine the prevalence of splenomegaly in PAH and assess whether it correlates with severity of disease and outcome. METHODS We identified subjects with either heritable or idiopathic PAH who had Dopple...

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idiopathic pulmonary arterial hypertension

cytometry analysis of BAL cells. Table 1 integrates information given in our published paper, clearly demonstrating that the number of BAL neutrophils was fair in our case series. This unfortunately prevented a definitive evaluation of whether polymorph nucleates represent a source of IL-17. Nonetheless, as shown in figure 1, in selected cases with a significant number of BAL neutrophils (two s...

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A case of severe pulmonary hypertension associated with common arterial trunk and VSD in a 9 years old child

Background: Common arterial trunk (CAT) is a rare congenital heart disease, and often leads to the early development of pulmonary hypertension and disability. Among the critical structural heart defects, the frequency of CAT is 3%, which reflects the severe hemodynamic disturbances. The natural course of the disease is characterized by a high mortality rate up to 88% during the first year of li...

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Quadriceps muscle fibre dysfunction in patients with pulmonary arterial hypertension

Despite improvements in disease targeted therapies, pulmonary arterial hypertension (PAH) is a progressive disease and PAH patients remain symptomatic [1]. Exercise intolerance is one of the main symptoms, which limit PAH patients in their daily life activities. Reduced exercise capacity is generally attributed to right ventricular dysfunction [1]. However, as with other cardiac and pulmonary d...

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ژورنال

عنوان ژورنال: Thorax

سال: 2014

ISSN: 0040-6376

DOI: 10.1136/thoraxjnl-2014-206260.150